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Experts from Brigham Young University in Utah discovered that addiction comes from an 'overcorrection' inside brain, a PsychCentral report said.

Using two separate drugs to shed weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you need to err assisting caution and allow FDA do its job and demand some research be done so your public is aware of the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say everything to keep people on his or her medications.

Researchers found that participants investing in this drug for a year, dropped a few pounds within four weeks and have kept the load off through the entire 56 weeks of the study. Contrave can be a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of more than one active ingredient, which can make them more efficient and safer.

Combo-pilling is the newest fad or even better the newest into the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is now popular is the fact that since right now there aren't any long term prescription diet pills that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures certainly are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise blood pressure levels and heart rate, and must not be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must 't be used in patients with uncontrolled high blood pressure level, as well as by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients on the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

"This could be the first drug I'm alert to that targets both appetite and reward centres inside brain," he explained.
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